detection of ctDNA mutations in plasma of colorectal cancer patients by PCR/SERS

Mastery Studying Ensures Right Private Protecting Gear Use in Simulated Medical Encounters of COVID-19

Introduction: The proper use of private protecting gear (PPE) limits transmission of significant communicable ailments to healthcare employees, which is critically necessary within the period of coronavirus illness 2019 (COVID-19). Nonetheless, prior research illustrated that healthcare employees often err throughout utility and elimination of PPE. The aim of this research was to find out whether or not a simulation-based, mastery studying intervention with deliberate observe improves appropriate use of PPE by physicians throughout a simulated medical encounter with a COVID-19 affected person.

Strategies: 

  • This was a pretest-posttest research carried out within the emergency division at a big, educational tertiary care hospital between March 31-April 8, 2020. A complete of 117 topics participated, together with 56 school members and 61 resident physicians. Previous to the intervention, all contributors acquired institution-mandated training on PPE use by way of a web based video and supplemental supplies.
  • Individuals accomplished a pretest abilities evaluation utilizing a 21-item guidelines of steps to appropriately don and doff PPE. Individuals had been anticipated to fulfill a minimal passing rating (MPS) of 100%, decided by an skilled panel utilizing the Mastery Angoff and Affected person Security standard-setting strategies. Individuals that met the MPS on pretest had been exempt from the tutorial intervention.
  • Testing occurred earlier than and after an in-person demonstration of correct donning and doffing strategies and 20 minutes of deliberate observe. The first end result was a change in evaluation scores of appropriate PPE use following our instructional intervention. Secondary outcomes included variations in efficiency scores between school members and resident physicians, and variations in efficiency throughout donning vs doffing sequences.

Outcomes: All contributors had a imply pretest rating of 73.1% (95% confidence interval [CI], 70.9-75.3%). College member and resident pretest scores had been related (75.1% vs 71.3%, p = 0.082). Imply pretest doffing scores had been decrease than donning scores throughout all contributors (65.8% vs 82.8%, p<0.001). Participant scores elevated 26.9% (95% CI of the distinction 24.7-29.1%, p<0.001) following our instructional intervention leading to all contributors assembly the MPS of 100%.

Conclusion: A mastery studying intervention with deliberate observe ensured the proper use of PPE by doctor topics in a simulated medical encounter of a COVID-19 affected person. Additional research of translational outcomes is required.

 

Multiplex detection of ctDNA mutations in plasma of colorectal most cancers sufferers by PCR/SERS assay 

Molecular diagnostic testing of KRAS and BRAF mutations has turn out to be crucial within the administration of colorectal most cancers (CRC) sufferers. Some progress has been made in liquid biopsy detection of mutations in circulating tumor DNA (ctDNA), which is a fraction of circulating cell-free DNA (cfDNA), however gradual evaluation for DNA sequencing strategies has restricted speedy diagnostics.

Different strategies reminiscent of quantitative PCR and extra lately, droplet digital PCR (ddPCR), have limitations in multiplexed capability and the necessity for costly specialised gear. Therefore, a sturdy, speedy and facile technique is required for detecting a number of ctDNA mutations to enhance the administration of CRC sufferers. To deal with this important drawback, herein, we suggest a brand new utility of multiplex PCR/SERS (surface-enhanced Raman scattering) assay for the detection of ctDNA in CRC, in a quick and non-invasive method to diagnose and stratify sufferers for efficient remedy.

Strategies: To discriminate ctDNA mutations from wild-type cfDNA, allele-specific primers had been designed for the amplification of three clinically necessary DNA level mutations in CRC together with KRAS G12V, KRAS G13D and BRAF V600E. Floor-enhanced Raman scattering (SERS) nanotags had been labelled with a brief and particular sequence of oligonucleotide, which may hybridize with the corresponding PCR amplicons. The PCR/SERS assay was applied by firstly amplifying the a number of mutations, adopted by binding with multicolor SERS nanotags particular to every mutation, and subsequent enrichment with magnetic beads. The mutation standing was evaluated utilizing a conveyable Raman spectrometer the place the fingerprint spectral peaks of the corresponding SERS nanotags point out the presence of the mutant targets. The tactic was then utilized to detect ctDNA from CRC sufferers beneath a blinded take a look at, the outcomes had been additional validated by ddPCR.

Outcomes: The PCR/SERS technique confirmed excessive specificity and sensitivity for genotyping CRC cell traces and plasma ctDNA, the place as few as 0.1% mutant alleles could possibly be detected from a background of plentiful wild-type cfDNA. The blinded take a look at utilizing 9 samples from superior CRC sufferers by PCR/SERS assay was validated with ddPCR and confirmed good consistency with pathology testing outcomes.

Conclusions: With ddPCR-like sensitivity but on the comfort of normal PCR, the proposed assay reveals nice potential in delicate detection of a number of ctDNA mutations for medical decision-making.

tumoritestacollo
tumoritestacollo

Omaveloxolone (RTA-408)

B3576-5 5 mg
EUR 247.2
Description: Omaveloxolone (RTA-408)

GPCR GPR86 Antibody

48382-100ul 100ul
EUR 399.6

GPCR GPR86 Antibody

48382-50ul 50ul
EUR 286.8

GPCR RDC1 Antibody

49041-100ul 100ul
EUR 399.6

GPCR RDC1 Antibody

49041-50ul 50ul
EUR 286.8

GPCR GPR65 Antibody

DF13937 100ul
EUR 420

GPCR TGR5 Antibody

DF14067 100ul
EUR 420

Anti-D-GPCR Antibody

A12058 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for D-GPCR Antibody (OR51E1) detection.tested for WB in Human.

D-GPCR Polyclonal Antibody

ABP51168-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

D-GPCR Polyclonal Antibody

ABP51168-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

D-GPCR Polyclonal Antibody

ABP51168-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

GPCR GPR86 Conjugated Antibody

C48382 100ul
EUR 476.4

GPCR RDC1 Conjugated Antibody

C49041 100ul
EUR 476.4

D-GPCR Polyclonal Antibody

ES2167-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

D-GPCR Polyclonal Antibody

ES2167-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Anti-D-GPCR antibody

STJ92705 200 µl
EUR 236.4
Description: Rabbit polyclonal to D-GPCR.

Anti-GPCR GPR40 Antibody

STJ501005 100 µg
EUR 571.2

Anti-GPCR GPR3 Antibody

STJ501253 100 µg
EUR 571.2

anti-GPCR GPR146

YF-PA21926 100 ug
EUR 483.6
Description: Rabbit polyclonal to Anti-GPCR GPR146

anti-GPCR MRGX2

YF-PA22009 50 ug
EUR 435.6
Description: Mouse polyclonal to Anti-GPCR MRGX2

anti-GPCR LOC51210

YF-PA22204 50 ul
EUR 435.6
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR LOC51210

YF-PA22205 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR LOC51210

YF-PA22206 100 ul
EUR 483.6
Description: Rabbit polyclonal to GPCR LOC51210

anti-GPCR LOC51210

YF-PA22207 100 ug
EUR 483.6
Description: Rabbit polyclonal to GPCR LOC51210

anti-GPCR 2037

YF-PA22241 50 ug
EUR 435.6
Description: Mouse polyclonal to Anti-GPCR 2037

anti-GPCR GPR110

YF-PA22867 50 ul
EUR 435.6
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR110

YF-PA22868 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR3

YF-PA23809 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR GPR3

anti-GPCR GPR3

YF-PA12103 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR GPR3

anti-GPCR GPR34

YF-PA12105 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR GPR34

anti-GPCR C5L2

YF-PA18412 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR C5L2

anti-GPCR SALPR

YF-PA18968 50 ul
EUR 435.6
Description: Mouse polyclonal to GPCR SALPR

anti-GPCR GPRC5D

YF-PA19735 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR GPRC5D

anti-GPCR GPR62

YF-PA26842 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR GPR62

anti-GPCR LOC51210

YF-PA26875 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR HM74

YF-PA15914 50 ug
EUR 435.6
Description: Mouse polyclonal to GPCR HM74

anti-GPCR SALPR

YF-PA26165 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR SALPR

anti-GPCR EX33

YF-PA26233 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR EX33

anti-GPCR GPRC5D

YF-PA26334 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR GPRC5D

anti-GPCR LGR7

YF-PA26522 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR LGR7

anti-GPCR LGR6

YF-PA26523 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR LGR6

anti-GPCR TAS1R1

YF-PA26658 50 ul
EUR 400.8
Description: Mouse polyclonal to GPCR TAS1R1

Anti-GPCR GPR40/FFAR1 Antibody

A01349-2 100ug/vial
EUR 352.8

Anti-GPCR LGR8/RXFP2 Antibody

A04848-1 100ug/vial
EUR 400.8

Anti-LGR6/Gpcr Lgr6 Antibody

A05990 100ul
EUR 476.4
Description: Rabbit Polyclonal LGR6/Gpcr Lgr6 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GPCR GPR7/NPBWR1 Antibody

A08247-1 100ug/vial
EUR 352.8

Anti-GPR151/Gpcr 2037 Antibody

A14582 100ul
EUR 476.4
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-GPR151/Gpcr 2037 Antibody

A30814 100ul
EUR 476.4
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in IF, WB and tested in Mouse, Rat.

Anti-GPCR GPR40 Antibody BIOTIN

STJ501006 100 µg
EUR 703.2

Anti-GPCR GPR40 Antibody FITC

STJ501007 100 µg
EUR 703.2

Anti-GPCR GPR3 Antibody BIOTIN

STJ501254 100 µg
EUR 703.2

Anti-GPCR GPR3 Antibody FITC

STJ501255 100 µg
EUR 703.2

Porcine GPCR ELISA Kit

EPG0026 96Tests
EUR 625.2

Rabbit GPCR ELISA Kit

ERTG0026 96Tests
EUR 625.2

Rat GPCR ELISA Kit

ERG0026 96Tests
EUR 625.2

Mouse GPCR ELISA Kit

EMG0026 96Tests
EUR 625.2

Monkey GPCR ELISA Kit

EMKG0026 96Tests
EUR 625.2

Human GPCR ELISA Kit

EHG0026 96Tests
EUR 625.2

Goat GPCR ELISA Kit

EGTG0026 96Tests
EUR 625.2

Bovine GPCR ELISA Kit

EBG0026 96Tests
EUR 625.2

Canine GPCR ELISA Kit

ECG0026 96Tests
EUR 625.2

Chicken GPCR ELISA Kit

ECKG0026 96Tests
EUR 625.2

DiscoveryProbe? GPCR Compound Library

L1025-.1 100 uL/well(10 mM solution)
EUR 5683.2

DiscoveryProbe? GPCR Compound Library

L1025-.25 250 uL/well(10 mM solution)
EUR 10221.6

DiscoveryProbe? GPCR Compound Library

L1025-5 5 mg/well
EUR 13284

Sheep GPCR ELISA Kit

ESG0026 96Tests
EUR 625.2

Anti-GPCR SALPR (1F10)

YF-MA18467 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR SALPR

Anti-GPCR EX33 (5C3)

YF-MA18601 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR EX33 (5B7)

YF-MA18602 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR EX33 (1D9)

YF-MA18603 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR GPR48 (8F6)

YF-MA18780 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR GPR48

Anti-GPCR GPRC5D (6D9)

YF-MA18788 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR GPRC5D

Anti-GPCR LOC51210 (6D7)

YF-MA19845 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR LOC51210

Anti-GPCR LGR7 (3E3)

YF-MA11622 100 ug
EUR 435.6
Description: Mouse monoclonal to GPCR LGR7

MicroRT tubing aligner, for easy alignment of MicroRT tubing onto goniometer base

RTA-1 1 UNIT
EUR 106
Description: MicroRT tubing aligner, for easy alignment of MicroRT tubing onto goniometer base

Guinea Pig GPCR ELISA Kit

EGG0026 96Tests
EUR 625.2

Anserini GPCR-APJ ELISA Kit

EAG0026 96Tests
EUR 625.2

anti-5-oxo-ETE GPCR

YF-PA22585 50 ug
EUR 435.6
Description: Mouse polyclonal to 5-oxo-ETE GPCR

Orphan GPCR SP9155 Agonist P518 (human)

H-5984.0500 0.5mg
EUR 588
Description: Sum Formula: C127H195N37O37; CAS# [600171-68-4] net

Orphan GPCR SP9155 Agonist P518 (human)

H-5984.1000 1.0mg
EUR 1023.6
Description: Sum Formula: C127H195N37O37; CAS# [600171-68-4] net

Orphan GPCR SP9155 Agonist P550 (mouse)

H-5986.0500 0.5mg
EUR 588
Description: Sum Formula: C126H195N37O37; CAS# [600171-70-8] net

Orphan GPCR SP9155 Agonist P550 (mouse)

H-5986.1000 1.0mg
EUR 1023.6
Description: Sum Formula: C126H195N37O37; CAS# [600171-70-8] net

DiscoveryProbe? GPCR/G protein-related Compounds Panel

L1009-5 5 mg/well
EUR 7242
Description: A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc.

CORNING® LSE™ MINI MICROCENTRIFUGE 0.20 ADAPTER FOR 6770-RT

6770-RTA.20 8/pk
EUR 56.4
Description: Lab Equipment; General Purpose Centrifuges (affliated brand)

CORNING® LSE™ MINI MICROCENTRIFUGE 0.25 ADAPTER FOR 6770-RT

6770-RTA.25 8/pk
EUR 56.4
Description: Lab Equipment; General Purpose Centrifuges (affliated brand)

CORNING® LSE™ MINI MICROCENTRIFUGE 0.5 ADAPTER FOR 6770-RT

6770-RTA.5 8/pk
EUR 56.4
Description: Lab Equipment; General Purpose Centrifuges (affliated brand)

Cell Meter™ Beta-Arrestin Translocation GPCR Signaling Kit

36390 100 Tests
EUR 781

Cell Meter™ Beta-Arrestin Translocation GPCR Signaling Kit

36391 200 Tests
EUR 989

CD11b Antibody Antibody

ABD2911 100 ug
EUR 525.6

ASAP1 antibody Antibody

DF8746 200ul
EUR 420

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 100 ug
EUR 525.6

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.08ML 0.08 ml
EUR 165

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.4ML 0.4 ml
EUR 379

Antibody

A1360-500 Ask for price

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 627.6

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 343.2

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 469.2

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 577.2

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 661.2

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

CLCN5 Antibody / CIC-5 antibody

RQ6462 100ug
EUR 419
Description: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-100ul 100ul
EUR 399.6

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-50ul 50ul
EUR 286.8

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-01mg 0,1 mg
EUR 321
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-1000ug 1000 ug
EUR 1539
Description: anti-CD22 monoclonal antibody

Antibody Pair to ApoA-V antibody

10R-1876 100 ul
EUR 781.2
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103034
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103035
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103036
  • EUR 577.20
  • EUR 159.60
  • EUR 1696.80
  • EUR 794.40
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatitis C Virus Antibody (HCV) Antibody

abx023924-1mg 1 mg
EUR 1446

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319902
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319903
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319904
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319906
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319907
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319908
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319914
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319915
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319916
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319929
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319930
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319931
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (HRP)

20-abx311666
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (FITC)

20-abx311667
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (Biotin)

20-abx311668
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein 210 Antibody (gp210) Antibody

abx233571-100ug 100 ug
EUR 577.2

Anti Deoxyribonucleic Acid Antibody (DNA) Antibody

abx411057-50ug 50 ug
EUR 710.4

Monoclonal NGF/proNGF Neutralizing Antibody Antibody

AMM06679G 0.05mg
EUR 633.6
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Goat anti- human Antibody^Polyclonal antibody

LSMab09896 100 ug
EUR 525.6

Antibody for Human alpha Tubulin Antibody

SPC-692D 0.1mg
EUR 424.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A390 0.1mg
EUR 481.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A488 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A565 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 565.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A594 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 594.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A633 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 633.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A655 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 655.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A680 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 680.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A700 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 700.

Antibody for Human alpha Tubulin Antibody

SPC-692D-ALP 0.1mg
EUR 472.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Alkaline Phosphatase.

Antibody for Human alpha Tubulin Antibody

SPC-692D-APC 0.1mg
EUR 478.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC .

Antibody for Human alpha Tubulin Antibody

SPC-692D-APCCY7 0.1mg
EUR 565.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC/Cy7.

Antibody for Human alpha Tubulin Antibody

SPC-692D-BI 0.1mg
EUR 475.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Biotin.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY350 0.1mg
EUR 496.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 350.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY405 0.1mg
EUR 483.6
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 405.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY488 0.1mg
EUR 471.6
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 488.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY594 0.1mg
EUR 474
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 594.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY633 0.1mg
EUR 468
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 633.

Antibody for Human alpha Tubulin Antibody

SPC-692D-FITC 0.1mg
EUR 470.4
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to FITC.

Antibody for Human alpha Tubulin Antibody

SPC-692D-HRP 0.1mg
EUR 465.6
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to HRP.

Antibody for Human alpha Tubulin Antibody

SPC-692D-P594 0.1mg
EUR 488.4
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to PE/ATTO 594.

Antibody for Human alpha Tubulin Antibody

SPC-692D-PCP 0.1mg
EUR 478.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to PerCP.

Medical interns’ reflections on their coaching in use of private protecting gear

Background: The present COVID-19 pandemic has demonstrated that non-public protecting gear (PPE) is crucial, to forestall the acquisition and transmission of infectious ailments, but its use is usually sub-optimal within the medical setting.

Coaching and training are necessary to make sure and maintain the secure and efficient use of PPE by medical interns, however present strategies are sometimes insufficient in offering the related data and abilities. The aim of this research was to discover medical graduates’ experiences of using PPE and determine alternatives for enchancment in training and coaching programmes, to enhance occupational and affected person security.

Strategies: This research was undertaken in 2018 in a big tertiary-care instructing hospital in Sydney, Australia, to discover medical interns’ self-reported experiences of PPE use, firstly of their internship. Reflexive teams had been performed instantly after theoretical and sensible PPE coaching, throughout hospital orientation. Transcripts of recorded discussions had been analysed, utilizing a thematic method that drew on the COM-B (functionality, alternative, motivation – behaviour) framework for behaviour.

Outcomes: 80% of 90 eligible graduates participated. Many interns had not beforehand acquired formal coaching within the particular abilities required for optimum PPE use and had developed probably unsafe habits. Their experiences as medical college students in medical areas contrasted sharply with advisable observe taught at hospital orientation and impacted on their potential to domesticate appropriate PPE use.

Conclusions: Undergraduate instructing must be according to finest observe PPE use, and embody sensible coaching that embeds appropriate and secure practices.

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